Now showing items 1-5 of 5

  • Dissection of Mechanisms Regulating the Drosophila Hedgehog Pathway 

    Shi, Qing (2012-07-20)
    Hedgehog (Hh) signaling is essential for both embryonic development and adult tissue homeostasis. Malfunction of Hh signaling pathway causes many human disorders including birth defects and cancers. In Drosophila, the ...
  • The Hippo Signaling Pathway in Organ Size Control and Regeneraton 

    Ren, Fangfang (2012-07-17)
    The Hippo (Hpo) signaling pathway controls cell growth, proliferation and apoptosis in both Drosophila and vertebrates. Our lab has previously demonstrated that Hpo signaling regulates gene expression by inhibiting a ...
  • Investigations into the Role of Paf1 Complex Proteins in Drosophila Ovaries 

    Chaturvedi, Dhananjay (2014-10-23)
    Over the past decade considerable interest has grown in epigenetics and chromatin modifications. The ability of two cells with identical genomes to have entirely different transcriptomes and therefore cellular behaviors ...
  • Studies of Smoothened in Hedgehog Signaling Pathway 

    Tong, Chao (2006-12-20)
    The Hedgehog (Hh) family of morphogens controls cell growth and patterning in both vertebrates and invertebrates. Malfunction of Hh signaling has been implicated in numerous human disorders. As the Hh signal transducer, ...
  • Studies of the Hippo Signaling Pathway 

    Yue, Tao (2012-08-13)
    How multicellular organisms control their growth to reach proper organ size during development is a fascinating question. Recent studies, initially from Drosophila, have identified the Hpo tumor suppressor pathway as a ...