Browsing by Subject "Genes, p53"
Now showing items 1-3 of 3
(2003-04-01)Xeroderma Pigmentosum (XP) is a rare genetic disorder characterized by extreme sensitivity to sunlight, and a profound predisposition to skin cancer due to defects in nucleotide excision repair (NER) of DNA. XP patients ...
(2005-05-03)When cells are challenged by genotoxic stress, the tumor suppressor protein p53 promotes adaptive responses, including cell cycle arrest, DNA repair, or apoptosis. How these distinct fates are specified through an action ...