Now showing items 1-4 of 4

  • Dynamic and kinetic investigations of SEM-5/SOS peptide interactions 

    li chieh Chen (2009-04-01)
    The dynamics of SEM-5 SH3 domain protein can provide an important insight into how structural dynamics contribute to protein function. This is important because solving the structure of protein alone only provides the ...
  • A general scaffold for the synthesis of cysiherbaine and its analogues 

    Chang Won Kang (2008-12-03)
    Dysiherbaine 1 and a select number of structurally related compounds have been shown to have selective effects on ionotropic glutamate receptors (iGluRs). iGluRs are essential components in the central nervous system (CNS); ...
  • A mechanism of activation of c-MET receptor tyrosine kinase 

    Payal Sheth (2006-06-23)
    c-MET receptor tyrosine kinase-mediated signaling governs numerous important cellular responses including cellular proliferation, differentiation, migration and apoptosis. Deregulation of these signals result in malignant ...
  • Structural studies of the YedU stress protein 

    Yonghong Zhao (2004-11-12)
    The knowledge of stress proteins is important for understanding stress response, pathology of a broad set of diseases, and the development of therapeutics. The Escherichia coli YedU stress protein, also known as Hsp31, ...