Now showing items 1-2 of 2

  • Biological studies of GPI-anchoring in Trypanosoma cruzi 

    Michele Anne Zacks (2007-04-24)
    Trypanosoma cruzi, a protozoan parasite transmitted to humans via triatomine\r\ninsects, causes chronic chagasic cardiomyopathy (CCM) in ~30% of infected individuals.\r\nThis dissertation sought to characterize T. cruzi’s ...
  • The nanomechanics of polycystin-1: A kidney mechanosensor 

    Liang Ma (2010-06-25)
    Mutations in polycystin-1 (PC1) can cause Autosomal Dominant Polycystic Kidney Disease (ADPKD), which is a leading cause of renal failure. The available evidence suggests that PC1 acts as a mechanosensor, receiving signals ...