Enzymatic mechanisms of HCO3 / CO2 assimilation in Neisseria gonorrhoeae

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Title: Enzymatic mechanisms of HCO3 / CO2 assimilation in Neisseria gonorrhoeae
Author: Cox, David L.
Abstract: Most strains of Neisseria gonorrhoeae require supplimental carbon dioxide (C0„ ) or bicarbonate (HCO ) for growth upon primary isolation . 14 1 In initial growth studies using ( C ) bicarbonate , Talley and Baugh demonstrated that most of the bicarbonate assimilated during the growth of the organism was found in the protein and nucleic acid fractions . Cox and Baugh reported that the Michaelis constant for HCO of partially purified phosphoenolpyruvate carboxylase (PEPCase ) from N^ . gonorrhoeae to be 0 .27 mM and concluded that this enzyme was probably not the direct cause of the organism's requirement for supplemental HCO , for growth . This Michaelis constant was several times lower than that of PEPCases from any other bacteria even those not requiring supplemental HCO _ for growth .
URI: http : / /hdl .handle .net /2346 /11143
Date: 1979-08

Citation

Cox, David L. Enzymatic mechanisms of HCO3 / CO2 assimilation in Neisseria gonorrhoeae. Doctoral dissertation, Texas Tech University. Available electronically from http : / /hdl .handle .net /2346 /11143 .

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