| dc.contributor |
Niederkorn , Jerry |
|
| dc.date |
2010 -07 -12T17 :32 :30Z |
|
| dc.date |
2010 -07 -12T17 :32 :30Z |
|
| dc.date |
2004 -01 -14 |
|
| dc.date.accessioned |
2013 -04 -17T19 :02 :33Z |
|
| dc.date.available |
2013 -04 -17T19 :02 :33Z |
|
| dc.date.issued |
2013 -04 -17 |
|
| dc.identifier |
|
|
| dc.identifier |
http : / /hdl .handle .net /2152 .5 /312 |
|
| dc.identifier.uri |
http : / /hdl .handle .net /2152 .5 /312 |
|
| dc.description |
Acanthamoeba spp . are ubiquitously distributed in the environment . The trophozoite form can infect the cornea and cause sight -threatening corneal inflammation known as Acanthamoeba keratitis . The pathogenic cascade of Acanthamoeba keratitis begins when Acanthamoebae bind to mannose expressed on traumatized corneas . Published reports indicate that mannose is upregulated on the corneal surface during wound healing . Experiments in laboratory animals have shown that corneal abrasion prior to infection is essential for generating Acanthamoeba keratitis . Furthermore , supernatants from Acanthamoeba |
|
| dc.format |
Electronic |
|
| dc.format |
application /pdf |
|
| dc.format |
born digital |
|
| dc.language |
en |
|
| dc.subject |
Eye Infections , Parasitic |
|
| dc.subject |
Acanthamoeba Keratitis |
|
| dc.subject |
Protozoan Proteins |
|
| dc.title |
Acanthamoeba spp . Secrete a Mannose -induced Protein That Correlates With Ability to Cause Acanthamoeba Keratitis |
|
| dc.type |
Text |
|
| dc.type |
dissertation |
|