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Abstract:
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This dissertation focuses toward finding two new avenues to explore the properties of ionic liquids (ILs ) . First , ILs has been used as a novel , and advantageous supporting electrolytes in nanopore stochastic sensing technology . Here , the sensing element is the alpha hemolysin protein , while a solution containing an ionic liquid will be used as the background electrolyte , instead of the typical used NaCl /KCl solution . This method employs single -channel recording with the planar lipid bilayer technique , where current modulation represents individual binding events . In this study , a useful means of implementing IL salt solutions will be demonstrated . Specifically , its great enhancements of sensitivity and selectivity of the nanopore for some analytes in stochastic sensing will be discussed . Further , the pH triggered ligand gating of alpha -hemolysin pore , by phosphonium IL will also be discussedThe goal of the second study is , use of IL as the stationary phase in capillary gas chromatography (GC ) , with thermal conductivity detector (TCD ) for the detection of water content in liquid samples . The detection and quantitation of the amount of water in 50 different solvent samples , with increased sensitivity will be presented . |