Implantable Drug Delivery System With In-plane Micropump

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dc.contributor Mhatre , Amit A en_US 2007 -08 -23T01 :55 :54Z 2011 -08 -24T21 :39 :35Z 2007 -08 -23T01 :55 :54Z 2011 -08 -24T21 :39 :35Z 2007 -08 -23T01 :55 :54Z January 2006 en_US
dc.identifier.uri http : / /hdl .handle .net /10106 /21
dc.description.abstract A MEMS based Implantable Drug Delivery System (IDDS ) is discussed . The heart of the system is an in -plane MEMS micropump enables us to make a compact , inexpensive system . A conceptual IDDS design is proposed . This design consists of an implantable unit which houses the micropump , electronic and power circuitry . This implantable unit is connected to a subcutaneous port via a silicone catheter . The subcutaneous port acts as a refillable reservoir . This leads to a reduction in unit volume and makes the system customizable . The IDDS pumps drug into surrounding tissue with the help of a MEMS -based micropump . The force generated by the MEMS actuator and the displacement of the tip is determined with the help of FEM simulations using ANSYS . The results from the displacement were verified experimentally . A lumped parameter model was made to estimate the flow rate through the outlet of the IDDS . Microfluidic interconnects to the micropump were fabricated and packaged . Packaging of interconnects uses processes like anodic bonding , microdrilling and fibre alignment . Future work will be focused on refining the IDDS model , conducting experiments to measure tip -force of pump actuators , experimental measurement of the flow generated , and implementation of electronic , RF and power components of the IDDS . en_US
dc.language.iso EN en_US
dc.publisher Biomedical Engineering en_US
dc.title Implantable Drug Delivery System With In -plane Micropump en_US
dc.type M .S . en_US


Implantable Drug Delivery System With In-plane Micropump. Available electronically from http : / /hdl .handle .net /10106 /21 .

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