Anti-viral Capacity Of Quillaja Saponaria Molina Extract Against Vaccinia And Herpes simplex Virus-1

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Title: Anti-viral Capacity Of Quillaja Saponaria Molina Extract Against Vaccinia And Herpes simplex Virus-1
Author: Spinks, Matthew Sean
Abstract: It is well known that Quillaja saponins have the ability to elicit a strong immune response when used as an adjuvant in an ISCOM matrix . However , to date , the antiviral capability of Quillaja saponins has not been documented . Using extracts from the Chilean Soap Bark Tree (Quillaja Saponaria Molina ) we document the anti -viral capacities of Quillaja saponins against HSV -1 and Vaccinia . The saponin was ineffective against Vaccinia Virus , however neutralized HSV -1 in a time and temperature dependent manner . In addition , Quillaja Saponins were determined capable of preventing cell -to -cell spread when introduced in solution to cell monolayers .
URI: http : / /hdl .handle .net /10106 /215
Date: 2007-08-23

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Anti-viral Capacity Of Quillaja Saponaria Molina Extract Against Vaccinia And Herpes simplex Virus-1. Available electronically from http : / /hdl .handle .net /10106 /215 .

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